The Eastern Division of the Cooperative Human Tissue Network (CHTN), which has been in existence for 21 years, continues its work of providing well-characterized biospecimens to investigators working in the fields of neoplasia, autoimmune disease, degenerative diseases and aging. Research projects include utilization of techniques of molecular biology, immunobiology, proteomics, genomics, and investigations of mutations, nucleic acid chemistry, and microRNA in disease. We are adapting our services to provide more specialized but still high-quality specimens to fill researcher needs by expanding our research base in the region.